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Anti-Spike ECD (SARS-CoV-2) monoclonal antibody (AT-ECD-35)

Key features:

  1. Monoclonal antibody from synthetic antibody libraries developed by AnTaimmu BioMed
  2. High affinity with SARS-CoV-2 spike protein, S1 domain
  3. Suitable for ELISA application
  4. IgG1 isotype

Datasheets   Contact us for MSDS

Description

Product name

Anti-Spike ECD (SARS-CoV-2) monoclonal antibody (AT-ECD-35)

Catalog number

ATBM-A-09

Source

Synthetic human library

MW (kDa)

150 kDa

Isotype

Human IgG1

Species Reactivity

SARS-CoV-2 spike protein, S1 domain

General notes

Background Information

Coronaviruses are enveloped positive-sense RNA viruses. The most prominent feature of coronaviruses is the club-shape spike projecting from the surface of the virion. Human coronaviruses, first identified in the mid-1960s, are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV), Severe Acute Respiratory Syndrome (SARS-CoV) and 2019 coronavirus disease (COVID-19), which was infected by SARS-CoV-2 virus and first reported from Wuhan, China, in 2019. The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Many studies have been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human angiotensin converting enzyme II (ACE2) receptor. The SARS-CoV spike (S) protein contains two subunits: the S1 subunit has a receptor binding domain (RBD) that interacting with host ACE2; the S2 subunit plays key parts in fusion between the viral and host cell membranes.

Properties

Form

Liquid

Storage instructions

Store at 4°C for up to 1 months from date of receipt. For long term storage, aliquot and store at -20°C. Avoid freeze-thaw cycles

Storage buffer

1 x PBS

Purification

Affinity purified by protein A

Contains

N/A

Conjugate

Unconjugated

Clonality

Monoclonal

Validated Applications

Applications Dilution
ELISA 1:1000~1:10000

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  • Anti-Spike ECD (SARS-CoV-2) monoclonal antibody (AT-ECD-37)

    Anti-Spike ECD (SARS-CoV-2) monoclonal antibody (AT-ECD-37)
  • Anti-Spike ECD (SARS-CoV-2) monoclonal antibody (AT-ECD-35)

    Anti-Spike ECD (SARS-CoV-2) monoclonal antibody (AT-ECD-35)

REFERENCES

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