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Anti-Spike ECD (SARS-CoV-2) Rabbit polyclonal antibody (AT-S-01)

Key features:

  1. Polyclonal antibody from whole rabbit serum produced by immunization with a purified recombinant SARS-CoV-2 ECD protein
  2. High affinity with spike (S) glycoprotein of SARS-COV-2
  3. Suitable for ELISA application

Datasheets   Contact us for MSDS

Description

Product name

Anti-Spike ECD (SARS-CoV-2) Rabbit polyclonal antibody (AT-S-01)

Catalog number

AT-S-01

Source

Rabbit

Species Reactivity

SARS-CoV-2 spike protein

General notes

Background Information

Coronaviruses are enveloped positive-sense RNA viruses. The most prominent feature of coronaviruses is the club-shape spike projecting from the surface of the virion. Human coronaviruses, first identified in the mid-1960s, are a large family of viruses that cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV), Severe Acute Respiratory Syndrome (SARS-CoV) and 2019 coronavirus disease (COVID-19), which was first reported from Wuhan, China, in 2019. The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Many studies have been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human angiotensin converting enzyme II (ACE2) receptor. The SARS-CoV spike (S) protein contains two subunits: the S1 subunit has a receptor binding domain (RBD) that interacting with host ACE2; the S2 subunit plays key parts in fusion between the viral and host cell membranes.

Properties

Storage instructions

Store at 4°C for up to 1 months from date of receipt. For long term storage, aliquot and store at -20°C. Avoid freeze-thaw cycles

Storage buffer

PBS

Purification

Affinity purified by protein A

Contains

N/A

Conjugate

Unconjugated

Clonality

Polyclonal

Validated Applications

Applications Dilution
ELISA 1:1000~1:10000

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